The importance of iodine

Iodine is an essential nutrient needed throughout life. Its primary role involves the synthesis of thyroid hormones, thyroxine (T4) and tri-iodothyronine (T3), which regulate central nervous system function, oxygen transport, growth, cell maturation, and metabolism. Ensuring sufficient iodine intake is particularly critical during conception, pregnancy, and infancy, supporting optimal foetal and infant neurological development and overall growth.

How much iodine do we need?

Iodine needs vary significantly over the lifespan, increasing substantially during pregnancy and lactation. During pregnancy, iodine requirements rise by approximately 65% to support foetal growth and compensate for increased iodine clearance. This is particularly important during the first trimester, as the foetus relies entirely on maternal iodine for thyroid hormone production. Lactation further elevates iodine demands to ensure breast milk adequately meets an infant’s needs during their first year.

Is there a risk of getting too much iodine?

Exceeding recommended iodine intake through diet alone is uncommon; however, excessive iodine consumption can occur through supplementation, medical treatments, or frequent consumption of iodine-rich foods such as seafood or seaweed. Symptoms of iodine toxicity can include nausea, vomiting, diarrhoea, delirium, and even shock. Excess iodine may also trigger thyroid dysfunction, such as hyperthyroidism, hypothyroidism, or goiter formation, emphasising the importance of moderation and medical guidance in supplementation.

Understanding iodine deficiency

While iodine deficiency is rare in Australia due to mandatory iodine fortification in bread, insufficient iodine intake can still pose health risks. Deficiency can result in clinical symptoms like hypothyroidism—fatigue, cold sensitivity, constipation, bradycardia, and goiter—or hyperthyroidism, marked by warm, moist skin, diarrhoea, and tachycardia. Chronic iodine deficiency can severely impact health, leading to impaired growth, infertility, altered metabolism, and neurological issues. Factors contributing to deficiency include increased iodine demands during pregnancy and lactation, inadequate dietary iodine, exposure to goitrogens (compounds that interfere with iodine uptake), and geographical variation in soil iodine content. Additionally, deficiencies in selenium, iron, or vitamin A can exacerbate iodine deficiency by impairing thyroid hormone synthesis and iodine uptake.

Dietary sources of iodine

In Australia, iodised table salt is the most concentrated dietary iodine source, with half a teaspoon meeting the recommended daily adult intake of 150 micrograms (µg). Other iodine-rich foods include seafood and seaweed, making them beneficial additions to a balanced diet.

Understanding iodine's role and maintaining adequate intake through informed dietary choices ensures robust thyroid function and supports lifelong health and development.


References:

Australian Institute of Health and Welfare. (2018). Nutrition across the life stages. https://doi.org/10.25816/5ebcaca1fa7e2

Australian National Health and Medical Research Council. (2006a). Iodine. https://www.eatforhealth.gov.au/nutrient-reference-values/nutrients/iodine

Bender, D. A. (2014). Introduction to Nutrition and Metabolism. Taylor & Francis Group.

Candido, A. C., Azevedo, F. M., Silva, D. L. F., Ribeiro, S. A. V., & Castro Franceschini, S. do C. (2023). Effects of iodine supplementation on thyroid function parameter: Systematic review and meta-analysis. In Journal of Trace Elements in Medicine and Biology (Vol. 80). Elsevier GmbH. https://doi.org/10.1016/j.jtemb.2023.127275

Food Standards Australia New Zealand. (n.d.-a). Australian Food Composition Database - Release 2.0. Iodine. Retrieved April 4, 2025, from https://afcd.foodstandards.gov.au/foodsbynutrientsearch.aspx?nutrientID=I

Giannocco, G., Kizys, M. M. L., Maciel, R. M., & de Souza, J. S. (2021). Thyroid hormone, gene expression, and Central Nervous System: Where we are. In Seminars in Cell and Developmental Biology (Vol. 114, pp. 47–56). Elsevier Ltd. https://doi.org/10.1016/j.semcdb.2020.09.007

Gibney, M., Lanham-New, S. A., Cassidy, A., & Vorster, H. H. (2009). Introduction to Human Nutrition. John Wiley & Sons, Incorporated.

Gropper, S. S., & Smith, J. L. (2021). Advanced Nutrition and Human Metabolism. Cengage.

Næss, S., Aakre, I., Strand, T. A., Dahl, L., Kjellevold, M., Stokland, A. E. M., Nedrebo, B. G., & Markhus, M. W. (2023). Infant iodine status and associations with maternal iodine nutrition, breast-feeding status and thyroid function. British Journal of Nutrition, 129(5), 854–863. https://doi.org/10.1017/S0007114522001465

Rigutto-Farebrother, J. (2023). Optimizing Growth: The Case for Iodine. In Nutrients (Vol. 15, Issue 4). MDPI. https://doi.org/10.3390/nu15040814

Whitney, E., Rolfes, S. R., & Crowe, T. (2022). Understanding Nutrition. Cengage Learning Australia.

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